What's the main difference between saying "Are you sure?" and "Are you serious?" Or are they all interchangeable?

Native speaker’s answer
Rebecca
The main difference between "are you sure?" and "are you serious?" is that "are you sure?" is asking if someone is certain about something, whereas "are you serious?" is asking if someone is being honest and not joking. Ex: I'm not joking, Tim. I'm being serious. I want to break up. Ex: Are you seriously leaving? Ex: Are you sure you want to leave? Ex: She's sure that she wants to move to Canada.