phosphorylate Definition
to add a phosphate group to a molecule, especially to a protein or a nucleotide.
Using phosphorylate: Examples
Take a moment to familiarize yourself with how "phosphorylate" can be used in various situations through the following examples!
Example
The enzyme phosphorylates the substrate.
Example
Protein phosphorylation is a common post-translational modification.
Example
ATP is used to phosphorylate glucose during glycolysis.
phosphorylate Synonyms and Antonyms
Synonyms for phosphorylate
Phrases with phosphorylate
a series of sequential phosphorylation reactions that amplify and transmit signals within cells
Example
The MAPK pathway is a well-known example of a phosphorylation cascade.
a specific amino acid residue on a protein that can be phosphorylated by a kinase
Example
The serine residue at position 473 is a key phosphorylation site on Akt.
the level of phosphorylation of a protein or a set of proteins in a cell or tissue
Example
The phosphorylation state of AMPK is regulated by various kinases and phosphatases.
Summary: phosphorylate in Brief
'Phosphorylate' [fɒs.fər.ɪ.leɪt] means to add a phosphate group to a molecule, especially to a protein or a nucleotide. It is a common post-translational modification that regulates protein activity and signaling pathways. Examples include 'The enzyme phosphorylates the substrate.' and 'ATP is used to phosphorylate glucose during glycolysis.' Phrases like 'phosphorylation cascade' and 'phosphorylation site' denote specific contexts in which phosphorylation occurs.
