What does "screw with someone/something" mean?

Native speaker’s answer
Rebecca
"Screw with someone/something" means to alter something improperly on purpose; try and ruin or sabotage someone/something intentionally. When he says, "don't screw with my dream," he means that don't try and ruin his dream. Ex: Don't screw with me! Ex: He keeps trying to screw with me. Ex: Someone screwed with the t.v.